〒981-3213 宮城県仙台市泉区南中山2-38-3

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E-mail:clinic@okabeclinic.net


院長の英文原著論文(48論文)

1. Mussell, M.J., Nakazono, Y., Miyamoto, Y., Okabe, S. and Takishima, T. 1990. Distinguishing normal and abnormal tracheal breathing sounds by principal component analysis. Japanese Journal of Physiology 40:713-721.

2. Satoh, M., Hida, W., Chonan, T., Miki, H., Iwase, N., Taguchi, O., Okabe, S., Kikuchi, Y. and Takishima, T. 1991. Role of hypoxic drive in regulation of postapneic ventilation during sleep in patients with obstructive sleep apnea. Am. Rev. Respir. Dis. 143:481-485.

3. Chonan, T., Okabe, S., Hida, W., Izumiyama, T., Kikuchi, Y. and Takishima, T. 1991. Inhomogeneous response of expiratory muscle activity to cold block of the ventral medullary surface. J. Appl. Physiol. 71:1723-1728.

4. Chonan, T., Hida, W., Okabe, S., Izumiyama, T., Sakurai, M. and Takishima, T. 1991. Effects of focal cooling of the ventral medullary surface on breathing pattern and blood pressure in dogs. Respiration Physiology 83:77-86.

5. Okabe, S., Chonan, T., Hida, W., Satoh, M., Taguchi, O., Kikuchi, Y., Miki, H., Iwase, N. and Takishima, T. 1991. Genioglossus and inspiratory pump muscle activity during hypoxia, hypercapnia and sleep in patients with obstructive sleep apnea. Advances in the biosciences 79:215-217.

6. Chonan, T., Okabe, S., Hida, W., Izumiyama, T., Sato, M., Sakurai, M., Kikuchi, Y. , Iwase, N., Taguchi, O, Miki, H. and Takishima, T. 1991. Effects of localized cooling of the ventral medullary surface (VMS) on expiratory muscle activity. Advances in the biosciences 79:73- 75.

7. Sato, M., Chonan, T., Hida, W., Okabe, S., Miki, H. , Taguchi, O. ,Kikuchi, Y. , Iwase, N., Miura, C. and Takishima, T. 1991. Load compensation to postural change in patients with obstructive sleep apnea. Advances in the biosciences 79:211-213.

8. Taguchi, O., Kikuchi, Y., Hida, W., Iwase, N., Sato, M., Okabe, S., Chonan, T. and Takishima, T. 1991. PGE2 inhalation increased dyspnea during exercise in normal subjects. Advances in the biosciences 79:355-357.

9. Taguchi, O., Kikuchi, Y., Hida, W., Iwase, N., Okabe, S., Chonan, T. and Takishima, T. 1992. Prostaglandin E2 inhalation increases the sensation of dyspnea during exercise. Am. Rev. Respir. Dis. 145:1346-1349.

10. Iwase, N., Kikuchi, Y., Hida, W., Miki, H., Taguchi, O., Satoh, M., Okabe, S. and Takishima, T. 1992. Effects of repetitive airway obstruction on O2 saturation and systemic and pulmonary arterial pressure in anesthetized dogs. Am. Rev. Respir. Dis. 146:1402-1410.

11. Chonan, T., Hida, W., Okabe, S., Chung, Y.,Kikuchi, Y. and Takishima, T. 1992. Does sustained hypoxia have biphasic effects on the sensation of dyspnea? In: Control of breathing and its modeling perspective, Y Honda eds. Plenum Press, New York, pp.183-186.

12. Hida, W., Okabe, S., Ebihara, S., Chonan, T., Kikuchi, Y.and Takishima, T. 1992. Serial submental stimulation during sleep in patients with obstructive sleep apnea. In: Control of breathing and its modeling perspective, Y. Honda eds. Plenum Press, New York, pp.337-340.

13. Kikuchi, Y., Sakurai, M., Hida, W., Okabe, S., Chung, Y., shindoh, C., Chonan, T., Kurosawa, H. and Takishima, T. 1992. Effects of changes in breathing pattern on the sensation of dyspnea during inspiratory loaded breathing. In: Control of breathing and its modeling perspective, Y. Honda eds. Plenum Press, New York, pp.405-408.

14. Satoh, M., Hida, W., Chonan, T., Okabe, S., Miki, H., Taguchi, O., Kikuchi, Y. and Takishima, T. 1993. Effects of posture on carbon dioxide responsiveness in patients with obstructive sleep apnoea. Thorax 48:537-541.

15. Okabe, S., Chonan, T., Hida, W., Satoh, M., Kikuchi, Y. and Takishima, T. 1993. Role of chemical drive in recruiting upper airway and inspiratory intercostal muscles in patients with obstructive sleep apnea. Am. Rev. Respir. Dis. 147:190-195.

16. Hida, W., Shindoh, C., Miki, H., Kikuchi, Y., Okabe, S., Taguchi, O., Takishima, T. and Shirato, K. 1993. Prevalence of sleep apnea among Japanese industrial workers determined by a portable sleep monitoring system. Respiration 60:332-337.

17. Okabe, S., Hida, W., Kikuchi, Y., Kurosawa, H., Midorikawa, J., Chonan, T., Takishima, T. and Shirato, K. 1993. Upper airway muscle activity during sustained hypoxia in awake humans. J. Appl. Physiol. 75:1552-1558.

18. Okabe, S., Hida, W., Kikuchi, Y., Taguchi, O., Takishima, T. and Shirato, K. 1994. Upper airway muscle activity during REM and non-REM sleep of patients with obstructive apnea. Chest 106:767-773.

19. Hida, W., Okabe, S., Miki, H., Kikuchi, Y., Taguchi, O., Takishima, T. and Shirato, K. 1994. Effects of submental stimulation for several consecutive nights in patients with obstructive sleep apnoea. Thorax 49:446-452.

20. Kikuchi, Y., Okabe, S., Tamura, G., Hida, W., Homma, M., Shirato, K. and Takishima, T. 1994. Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma. N. Engl. J. Med. 330:1329-1334.

21. Midorikawa, J., Kikuchi, Y., Taguchi, O., Hida, W., Okabe, S., Takishima, T. and Shirato, K. 1994, Effects of prostaglandin E2 inhalation on hypercapnic response in normal subjects. Am. J. Respir. Crit. Care Med. 150:1592-1597.

22. Mizusawa,A., Ogawa, H., Kikuchi, Y., Hida, W., Kurosawa, H., Okabe, S., Takishima, T. and Shirato, K. 1994. In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia. J. Physiology 478:55-65.

23. Okabe, S., Gustaw, W. and Kubin L. 1994. Role of GABAB receptors in the control of hypoglossal motoneurons in vivo. NeuroReport 5:2573-2576.

24. Hida, W., Okabe, S., Miki, H., Kikuchi, Y., Kurosawa, H., Takishima, T. and Shirato, K. 1995. Submental stimulation an supraglottic resistance during mouth breathing. Respiration Physiology 101:79-85.

25. Hida, W., Kurosawa, H., Okabe, S., Kikuchi, Y., Midorikawa, J., Chung, Y., Takishima, T. and Shirato, K. 1995. Hypoglossal nerve stimulation affects the pressure-volume behavior of the upper airway. Am. J. Respir. Crit. Care Med. 151:455-460.

26. Okabe, S., Hida, W., Kikuchi, Y., Taguchi, O., Ogawa, H., Mizusawa, A., Miki, H. and Shirato, K. 1995 Role of hypoxia on increased blood pressure in patients with obstructive sleep apnoea. Thorax 50:28-34.

27. Okabe, S., Hida, W., Chonan, T., Izumiyama, T., Kikuchi, Y., Takishima, T. and Shirato, K. 1995 Effect of intramedullary procaine injection on tracheal tone and phrenic neurogram. Respiration Physiology 99:89-96.

28. Hida, W., Kikuchi, Y., Okabe, S., Miki, H., Kurosawa, H. and Shirato, K. 1996. CO2 response for the brain stem artery blood flow velocity in man. Respiration Physiology 104:71 -75.

29. Okabe, S. and Kubin, L. 1996 Role of 5HT1 receptors in the control of hypoglossal motoneurons in vivo. Sleep 19: s150-s153.

30. Midorikawa, J., Hida, W., Taguchi, O., Okabe, S., Kurosawa, H., Mizusawa, A., Ogawa, H., Ebihara, S., Kikuchi, Y. and Shirato, K. 1997. Lack of ventilatory threshold in patients with chronic obstructive pulmonary disease. Respiration 64: 76-80.

31. Fenik, V., Kubin, L., Okabe, S., Pack, A. I. and Davies, R. O. 1997 Differential sensitivity of laryngeal and pharyngeal motoneurons to iontophoretic application of serotonin. Neuroscience 81: 813-819.

32. Okabe, S., Mackiewicz, M. and Kubin, L. 1997. Serotonin receptor mRNA expression in the hypoglossal motor nucleus. Respiration Physiology 110: 151-160.

33. Okabe, S., Sanford, L. D., Veasey, S. C. and Kubin, L. 1997. Pontine injections of nitric oxide synthase inhibitor, L-NAME consolidate episodes of REM sleep in the rat. Sleep research online 1: 41-48.

34. Taguchi O., Hida, W., Okabe, S., Ebihara, S., Ogawa, H., Kikuchi, Y., Shirato, K. 1997. Improvement of exercise performance with short-term nasal continuouos positive airway pressure in patients with obstructive sleep apnea. Tohoku J. Exp. Med. 183: 45-53.

35. Chonan, T., Okabe, S., Hida, W., Satoh, M., Kikuchi, Y., Takishima, T., and Shirato, K. 1998. Influence of sustained hypoxia on the sensation of dyspnea. Japanese Journal of Physiology 48: 291-295.

36. Ye Tun, Okabe, S., Hida, W., Kurosawa, H., Tabata, M., Kikuchi, Y. and Shirato, K. 1999. Nocturnal blood pressure during apnoeic and ventilatory periods in patients with obstructive sleep apnoea. Eur. Respir. J. 14: 1271-1277.

37. Wu, D., Hida, W., Kikuchi, Y., Okabe, S., Kurosawa, H., Ogawa, H. and Shirato, K. 1999. Volume-pressure properties of the upper airway in normal subjects and patients with obstructive sleep apnoea. Respirology 4: 69-75.

38. Ye Tun, Hida, W., Okabe, S., Kikuchi, Y., Kurosawa, H., Tabata, M. and Shirato, K. 2000. Effects of nasal continuous positive airway pressure on awake ventilatory responses to hypoxia and hypercapnia in patients with obstructive sleep apnea. Tohoku J. Exp. Med. 190: 157-168.

39. Onodera, H., Okabe, S., Kikuchi, Y., Tsuda, T. and Itoyama, Y. 2000. Impaired chemosensitivity and perception of dyspnoea in parkinson's disease. Lancet 356:739-740.

40. Ye Tun, Hida, W., Okabe, S., Kikuchi, Y., Kurosawa, H., Tabata, M. and Shirato, K. 2000. Inspiratory effort sensation to added resistive loading in patients with obstructive sleep apnea. Chest 118: 1332-1338.

41. Onodera, H., Okabe, S., Kikuchi, Y., Tsuda, T. and Itoyama, Y. 2000. Parkinson's disease and impaired chemosensitivity to hypoxia. Lancet 356: 2099.

42. Tabata, M., Kurosawa, H., Kikuchi, Y., Hida, W., Ogawa, H., Okabe, S., Tun, Y., Hattori, T., Shirato, K. 2001. Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats. Am. J. Physiol. 281: R1411-R1419.

43. Hida, W., Ye Tun, Kikuchi, Y., Okabe, S. and Shirato, K. 2002. Pulmonary hypertension in patients with chronic obstructive pulmonary disease: recent advances in pathophysiology and management. Respirology 7: 3-13.

44. Tsuda, T., Onodera, H., Okabe, S., Kikuchi, Y. and Itoyama, Y. 2002. Impaired chemosensitivity to hypoxia is a marker of multiple system atrophy. Ann. Neurol. 52:367- 371.

45. Ye Tun, Hida, W., Okabe, S. Ogawa, H., Kikuchi, Y., Oikawa, M., Kitamuro, T. and Shirato, K. 2003. Can nasal continuous positive airway pressure decrease clinic blood pressure in patients with obstructive sleep apnea? Tohoku J. Exp. Med. 201: 181-190.

46. Suzuki, M., Ogawa, H., Okabe, S., Yagi, T., Horiuchi, A., Okubo, M., Ikeda, K., Hida, W., Kobayashi, T. 2004. The effect of upper airway structural changes on central chemosensitivity in obstructive sleep apnea-hypopnea. Sleep and brething 8:73-83.

47. Suzuki, M., Ogawa, H., Okabe, S., Horiuchi, A., Okubo, M., Ikeda, K., Hida, W., Kobayashi, T. 2005. Digital recording and analysis of esophageal pressure for patients with obstructive sleep apnea-hypopnea syndrome. Sleep Breath 9:64-72.

48. Takayanagi, M., Okabe, S., Yamamoto, K., Komatsu, J., Suzuki, R., Kitamura, T., Ohura, T. 2017. kline-Levin syndrome elicited by encephalopathy with rebersible splenial lesion. Pediatrics International 59:929-931.

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